Showing posts with label DNA profiling. Show all posts
Showing posts with label DNA profiling. Show all posts

23 November 2014

AncestryDNA Sale???

Image from AncestryDNA website

You didn't hear this from me, but I was on the phone with Ancestry.com's Tech Support today (very helpful as usual) and before I hung up, I asked if their DNA test was still $99. She said that yes, it was to which I replied that I thought there might be some holiday specials.  Now, she didn't say anything definitive, but she "suggested" that I check the pricing on Black Friday.

Since the start of their DNA project, I have been cynical (or maybe the right word is skeptical) about their early results.  After all, it's hard to tell someone who is obviously of Asian descent that they were 98% Scandinavian.  Now I don't know if they tried to get away with that result specifically, but I do know that the early results were, at best, questionable. But after reading Judy G. Russell, Blaine T. Bettinger, Roberta Estes and others, Ancestry seems to have gotten their act together. They've even tweaked their autosomal results creating a significant trimming of possible matches. Nice job Ancestry!!  

As a result of all this and other factors, I'll certainly check them out again this Friday and see if the "hint" from Tech Support pans out. Or should I say the "shaky leaf" from Tech Support!!

By the way, my original issue was resolved...I think!
I'll leave you with my new mantra: "Climb YOUR tree!"


05 June 2014

Ancestry.com closes several services

[caption id="" align="alignleft" width="75"]Ancestry.com Ancestry.com (Photo credit: Wikipedia)[/caption]

Ancestry.com is shutting down a number of their services.  Of course, they put a positive spin on it by saying "Ancestry.com focuses on core offerings."  So it's half-full versus half-empty.  Either way, if you're fond of any of these services, it's time to plan!

 

Here's a link to the full story right from the horse's mouth: Ancestry.com Focuses on Core Products

 

Long ago I was a subscriber to MyFamily and I was fairly active.  If I remember, at the time it wasn't an Ancestry product.  I "almost" used MyCanvas but never completed the one project I started.

[caption id="" align="alignright" width="89"]English: Paintbrush drawn Icon for Portal Mol ... English: Paintbrush drawn Icon for Portal Mol Anthro (Photo credit: Wikipedia)[/caption]

Interestingly, what is not in the headline is that the only DNA testing they will continue is autosomal.  They've discontinued Y-DNA and mtDNA testing.  I wonder what the back-story is on that!!

 

Read their article to get the low-down.  In my opinion, other than the Y- and mt- DNA tests, I don't think the other products will be sorely missed.  We'll have to wait to see to what extent the wailing and gnashing of teeth goes!

 

 

 
Enhanced by Zemanta

29 March 2014

DNA on a Personal Level I Didn't Expect!

One of the things I enjoy is teaching genealogy.  I think I have a pretty good handle on how and where to research, what sites to use, where to go for data that's not on the internet and other areas.   Other areas such as DNA and its place in someones research plan.
DNA is one subject in which I know enough to talk intelligently about it, but I'm far from being an expert.  As a matter of fact, when I use DNA as subject matter in one of my sessions, the first thing our of my mouth is the disclaimer that I'm not a doctor by even the farthest stretch of the imagination and that I'm just above a beginner in the area of DNA.
Animation of the structure of a section of DNA...
Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands. (Photo credit: Wikipedia)
So a few months ago, I was conducting a series of classes at a fairly large facility near here.  It consisted of 6 sessions every Tuesday for 6 weeks.  Since I had so much time to devote to a variety of genealogical subjects, I put my DNA slide into the program.  I even put DNA graphics on my desktop.  Not just a simple graphic but one that spun slowly to see the graphic in 360°.  I think it is the same graphic that I've included here.
After the session, a middle aged woman approached me at the front of the room and joined a few of the participants who were asking additional questions.  As usual, I try to take everyone in their turn as they come forward.  However, the woman was obviously upset, her eyes were welled up with tears.  I immediately thought I had said something offensive, something that didn't sit right with her.  Understand that any time I'm speaking to the public, I try my absolute best to remain apolitical, non-discriminatory and thoroughly "G" rated!  What am I going to do now?
When most of the folks had stepped away, I asked the woman to have a seat as her husband approached the table where we were sitting. Oh no... Is this going to get ugly?  What in the world could I possibly have said?
Once we were in a semi-private moment, I asked what I could do to help them.  I had absolutely no idea what was going to happen.  And what happened is absolutely not what I expected.
"Can you advise me about a personal issue," she said.  I have to admit that this is not the direction I wanted this to go in but certainly better than what I had feared!  But a "personal" issue???
Then the bombshell:  "My brother's body was found in his apartment last week and the Medical Examiner will not release it until I can prove that he is definitely my brother.  He has no dental records and he never had his fingerprints taken.  Is there some kind of DNA test that I could have done to help us?"
After the shock of her dilemma sunk in...not to mention the fact that she was asking ME for advice...I expressed my sympathies to her and her family for their loss. From a human perspective, I wanted to know more but I didn't want to appear to pry into any family issues.  I felt the most prudent thing to do was to give her my opinion.  First, I asked if she had another brother in the family and she did.  To me, the only solution from a DNA perspective was to have a Y-DNA test on each of her brothers.  Scientifically at least, the brothers should come back as a 100% match.  After a few minutes of explaining why that would work, she and her husband thanked me, and they quietly left the room. But not before I asked her to please keep me informed as to the outcome.
When I got home, I immediately got in touch with a few other researchers I know who were far more knowledgeable in this area.  Thankfully, I was assured that the suggestion I made would be effective.   About a week or so later, I received an e-mail from her to say that the body had been sent to Boston and the ME in Boston agreed to release the body to the family without going through the DNA tests. I didn't ask how they managed to get through all the bureaucracy and red tape.  To me, the fact that what was a very personal tragedy had been resolved was enough for me.  She had a service for him a few days prior to the note she sent and was able to bury her brother in a family plot.  She was relieved and very grateful for my advice even though she thankfully didn't have to go through that process.
I'm still conducting classes and I still include the session on DNA.  I just hope that I'm not confronted with another situation involving a tragedy such as this one!
Enhanced by Zemanta

How will they find them a hundred years from now?

Believe me, I had enough trouble when I first met some people back in the 70's who were using hyphenated names.  I mean, you got married, the woman took the husband's family name, the family name was passed down to the children and all was right with the world.  This isn't necessarily a rant about various cultures and their naming conventions.  As a matter of fact, I respect naming conventions....when they are conventions!  Conventions such as a Swedish son taking the name of his father with the word "...son" appended: Anderson, Erikson, etc.  I can understand that.  Or the Spanish child with the father's surname first then the mother's surname hyphenated: Gonzalas Y Lupez.  No problems!
Thomas Huws Davies
Without getting into anyone's personal details, I'm amazed at the fact that there are hundreds and more than likely thousands of families that use whatever is convenient or sounds cool.  My wife works in a field where she has a great deal of contact with kids in the 1st to 4th grades.  She tells me many stories about kids this age who don't yet know their own names. Or they register for the programs under one name but the parents insist that the child is called by another name.  I'm not talking about calling "Thomas" "Tom".  It's more like calling "Jeremy" "Louis"!  This is not a case of using the middle name rather than the given name.  These "Names of Convenience" are nowhere to be found on any documentation at all!  Then there are the cases where a child is given an unpronounceable name with symbols integrated within the spelling!  I'm not kidding!  Using the "Thomas" example, she might see "Tom#as". Or "Anna-marble"  I'm not sure how the "Thomas" name would be pronounced (I could ask my wife before I post this) but I know that the second one is "Anna Dash Marble".  Anna Dash Marble?? Who??? (See the link below on creating fantasy names...I believe there are thousands of parents who are already there!)
And it doesn't stop there.  There are families that seem to change their family names on a whim. That alone will cause more genealogical brick walls than you can count.  But it will bring a fresh new meaning to the mantra "Speeling Duzn't Cownt"!
I'm glad I'm researching 16th, 17th, 18th and 19th century people in the 21st century.  I pity the genealogists of the 22nd century!  Break out the DNA tests...
Now if there's any reason for this generation to put together their own family histories, this might be it.  If we can today put together solid family trees with proper citations and proof arguments, then perhaps the genealogists of the future will only have to deal with a generation or two.  They may only have to work back to this generation, when genealogy and family research was easy!
Landing Page naming conventions
Landing Page naming conventions (Photo credit: Wikipedia)

Enhanced by Zemanta

07 February 2014

DNA on a Personal Level I Didn't Expect!

One of the things I enjoy is teaching genealogy.  I think I have a pretty good handle on how and where to research, what sites to use, where to go for data that's not on the internet and other areas.   Other areas such as DNA and its place in someones research plan.

DNA is one subject in which I know enough to talk intelligently about it, but I'm far from being an expert.  As a matter of fact, when I use DNA as subject matter in one of my sessions, the first thing our of my mouth is the disclaimer that I'm not a doctor by even the farthest stretch of the imagination and that I'm just above a beginner in the area of DNA.

[caption id="" align="alignright" width="290"]Animation of the structure of a section of DNA... Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands. (Photo credit: Wikipedia)[/caption]

So a few months ago, I was conducting a series of classes at a fairly large facility near here.  It consisted of 6 sessions every Tuesday for 6 weeks.  Since I had so much time to devote to a variety of genealogical subjects, I put my DNA slide into the program.  I even put DNA graphics on my desktop.  Not just a simple graphic but one that spun slowly to see the graphic in 360°.  I think it is the same graphic that I've included here.

After the session, a middle aged woman approached me at the front of the room and joined a few of the participants who were asking additional questions.  As usual, I try to take everyone in their turn as they come forward.  However, the woman was obviously upset, her eyes were welled up with tears.  I immediately thought I had said something offensive, something that didn't sit right with her.  Understand that any time I'm speaking to the public, I try my absolute best to remain apolitical, non-discriminatory and thoroughly "G" rated!  What am I going to do now?

When most of the folks had stepped away, I asked the woman to have a seat as her husband approached the table where we were sitting. Oh no... Is this going to get ugly?  What in the world could I possibly have said?

Once we were in a semi-private moment, I asked what I could do to help them.  I had absolutely no idea what was going to happen.  And what happened is absolutely not what I expected.

"Can you advise me about a personal issue," she said.  I have to admit that this is not the direction I wanted this to go in but certainly better than what I had feared!  But a "personal" issue???

Then the bombshell:  "My brother's body was found in his apartment last week and the Medical Examiner will not release it until I can prove that he is definitely my brother.  He has no dental records and he never had his fingerprints taken.  Is there some kind of DNA test that I could have done to help us?"

After the shock of her dilemma sunk in...not to mention the fact that she was asking ME for advice...I expressed my sympathies to her and her family for their loss. From a human perspective, I wanted to know more but I didn't want to appear to pry into any family issues.  I felt the most prudent thing to do was to give her my opinion.  First, I asked if she had another brother in the family and she did.  To me, the only solution from a DNA perspective was to have a Y-DNA test on each of her brothers.  Scientifically at least, the brothers should come back as a 100% match.  After a few minutes of explaining why that would work, she and her husband thanked me, and they quietly left the room. But not before I asked her to please keep me informed as to the outcome.

When I got home, I immediately got in touch with a few other researchers I know who were far more knowledgeable in this area.  Thankfully, I was assured that the suggestion I made would be effective.   About a week or so later, I received an e-mail from her to say that the body had been sent to Boston and the ME in Boston agreed to release the body to the family without going through the DNA tests. I didn't ask how they managed to get through all the bureaucracy and red tape.  To me, the fact that what was a very personal tragedy had been resolved was enough for me.  She had a service for him a few days prior to the note she sent and was able to bury her brother in a family plot.  She was relieved and very grateful for my advice even though she thankfully didn't have to go through that process.

I'm still conducting classes and I still include the session on DNA.  I just hope that I'm not confronted with another situation involving a tragedy such as this one!


Enhanced by Zemanta

29 November 2013

FamilyTreeDNA offers "Black Friday" Discounts

Sounds like every retailer in the universe is getting Black Friday Fever!  Here's a link to FamilyTreeDNA to read about what they're offering "today only"!

"Family Finder" is their terminology for an autosomal DNA test.  See?  "Family Finder" is easier to say!  But the difference between Y-DNA and mtDNA tests is this: Of the 23 pairs of chromosomes in the nucleus of the human gene, one pair is the sex chromosome the "X-X" or the "X-Y" .  Y-DNA is carried only by and passed along by males.  the mtDNA is actually outside the nucleus and is passed down only by the female but both males and females have the identical mtDNA.  So what about the fact that both Mon and Dad pass down various traits?  That's where autosomal DNA plays a part.  That is where the half contributed by Mom and combines with the half contributed by Dad.  This allows the science of DNA to predict (nothing is an absolute!) who your ancestors might be.

Avoid the throngs!  Shop on-line at FamilyTreeDNA!!

[caption id="" align="aligncenter" width="290"]Animation of the structure of a section of DNA... Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands. (Photo credit: Wikipedia)[/caption]

25 November 2013

23andMe Ordered to Shut Down

[caption id="" align="alignleft" width="250"]Image representing 23andMe as depicted in Crun... Image via CrunchBase[/caption]

[caption id="" align="alignright" width="290"]Animation of the structure of a section of DNA... Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands. (Photo credit: Wikipedia)[/caption]

By now I'm sure that many of you have seen the news that the DNA testing company, 23andMe, has been ordered by the FDA to cease and desist. Not a good sign! The government has been trying to get them to cooperate with a few demands that, in my opinion, are quite reasonable. Apparently this has been going on for a while. I plan on doing a little more reading about it and adding the information to this post. From what I understand so far, the crux of the matter is that the government wants them to explain how they disseminate the results of the DNA studies to people who may or may not use the information properly without the advice of a doctor. What if there's a false positive in a BRAC1 or BRAC2 test for breast cancer. The resulting anguish would be inexcusable until a doctor ran the appropriate tests. Worse, if the test was a false negative, how long would someone who actually had the faulty genes go without getting a more thorough, doctor supervised test/exam?

It's a big deal, for sure. And there'll be much more about this. There a millions of investment dollars at stake, not to mention the pall cast over the entire commercial DNA testing industry.

Stay tuned!

[caption id="" align="alignright" width="158"]Fda Fda (Photo credit: Wikipedia)[/caption]

Related articles

22 November 2013

Quick Note! FamilyTreeDNA Offers Huge Discount on All Tests

Just a quick note:  I found this in my backlogged e-mail tonight.  Click "Continue reading" to activate this link: http://bit.ly/1bd0Elo.  For a short period of time, FamilyTreeDNA is offering significant discounts on a variety of tests but the orders need to be placed and paid by December 31, 2013.

Let me know what you think!

[polldaddy poll=7587544]

[caption id="" align="aligncenter" width="203"]My Neanderthal DNA My Neanderthal DNA (Photo credit: jurvetson)[/caption]

09 October 2013

Hope for Ancestry DNA Testing???

The title of their blog is "Coming Soon - Ancestry DNA is Evolving".  So I'll post this for the benefit of those who have paid the piper and came back with far from satisfactory results: Native Americans who are told they are 97% Scandinavian, for example!   If I had a nickel for every complaint I've seen....well, you know!!

It seems to me that the first rush of tests that were done at Ancestry produced results based on a very small data base.  Eventually, they were able to purchase a large data base from Sorenson Molecular Genetic Genalogy to help them fine tune their analyses.  We'll see!

 

There's a DNA blog which I've recommended before.  II have to mention Roberta Estes who, I believe, is one of the premiere experts and writes a very down-to-earth blog called "DNAeXplained-Genetic Genealogy".  She has fielded hundreds of the complaints about AncestryDNA and handles them well.   She the right one to follow for your own "personal" course in genetic DNA.  Most of her blogs are not only informative but they're written in the English that most of us speak (not highly technical "scientist-speak") and always injects a bit of humor.